Uncommon Immunotherapy Side Effects

By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 30 November 2016

A recent report in the prestigious New England Journal of Medicine (NEJM), has spawned reports like this one, regarding the risk of death in patients treated with combination checkpoint treatments. The first author of the NEJM story is MRA-funded investigator, Doug Johnson at Vanderbilt.

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Championing Collaboration

By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 30 November 2016

Some have the impression that cancer researchers, whether in academia or in industry, toil away in isolation. While there are certainly scientists who work best on their own, collaboration among researchers has become increasingly common, with a goal of achieving the most promising results in the shortest time frame.

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MRA Funded Melanoma Researchers Led Discussions at 2016 Annual Meeting of the Society for Immunotherapy of Cancer

By Pamela Goldsmith, MRA Director of Communications | 30 November 2016

MRA Director of Communications Melanoma Research Alliance (MRA) investigators and other melanoma researchers had a significant presence at this year’s annual meeting of the Society for Immunotherapy of Cancer (SITC) held in National Harbor, Maryland. A key forum for scientific exchange and enlightenment in the cancer immunotherapy field, the conference...

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To Screen or Not to Screen (for Skin Cancer) – Reframing the Question

By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 29 July 2016

To screen or not to screen actually isn’t the question  While an adaptation of Hamlet’s famous phrase may capture the headlines on whole-body skin checks, a deeper dive gets us closer to questions of life and death.

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Highlights from the National Cancer Moonshot Summit

By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 7 July 2016 In Events, News

The National Cancer Moonshot was announced by President Obama in his State of the Union Address in January 2016 and VP Biden was charged with spearheading the effort. Few would disagree with Mr. Biden’s selection as leader given the personal experience he and his family endured with the loss of...

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Understanding Immunotherapy Part 3: CTLA-4

By Amrita Bhatt, MRA Intern | 15 June 2016 In Science, Treatment

Now that you’ve read our background on immunotherapy and learned about PD-1, it’s time to focus on another protein that plays a key role in cancer development, CTLA-4. What is CTLA-4? In addition to displaying PD-1 on the cell surface, T cells also display CTLA-4.

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Research Q&A: Dr. Tim Bullock

21 March 2016 In Science

In the latest blog post, we chatted with the University of Virginia’s Tim Bullock, Ph.D., a tumor immunologist in the Pathology Department and MRA-funded investigator. Read on to learn what he has to say about melanoma research and prevention efforts.

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Understanding Immunotherapy Part 2: PD-1

By Amrita Bhatt, MRA Intern | 17 February 2016 In Science, Treatment

Now that we’ve provided a brief background on immunotherapy, it’s time to dive more deeply into the subject. In the second installment of this blog series, we’ll be examining PD-1, a protein that plays a crucial role in cancer’s ability to hide from our immune systems. What is PD-1? PD-1...

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Researcher Q&A: Dr. John D’Orazio

7 January 2016 In Science

In the latest blog post, we chatted with the University of Kentucky’s John D’Orazio, M.D., Ph.D., a pediatric hematologist oncologist, and a 2015 MRA grant awardee. Read on to learn what he has to say about melanoma research and prevention efforts.

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