Acral Melanoma Model Catalog

In a collaborative effort to facilitate research focused on acral melanoma, MRA has created an Acral Melanoma Model Catalog of cell lines and patient-derived xenograft (PDX) models from various institutions worldwide. The catalog includes models created by researchers at University of Colorado, Memorial Sloan Kettering Cancer Center, Wistar Institute, Yale University, University of Zurich, the Queensland Institute of Medical Research in Australia, amongst others. 

The catalog will serve as a launching pad for researchers who want to study acral melanoma – providing awareness of preclinical models that have been created by other research laboratories and avoiding the timely process of creating new models from scratch. Please note that model exchanges between research laboratories are not guaranteed and in most cases would require an MTA between institutions and potentially an approved model use research request. MRA’s intent is to advance research on acral melanoma by building awareness and encouraging collaboration within the melanoma research community.

MRA’s Acral Melanoma Model Catalog provides basic information such as demographics, the oncogenomic profile, and the different clinical features of each model. The catalog also includes contact information and details on how to access, maintain, and grow each model. The MRA aims to keep updating the list of available acral melanoma models as they become available. 

You can navigate through Tableau (below) to find acral cell lines with specific mutations. Click here for more detailed genomic and clinical information on all available acral cell lines and contact information.

Questions should be sent to Joan Levy, PhD.