Can We Combine Immunotherapy and Targeted Therapy for Better Results?
Researchers are now considering how to build upon the success of immune-based and targeted therapies to help even more patients live longer, healthier lives. This month, several studies reported on efforts to combine PD-1 based immunotherapy with BRAF/MEKi targeted therapy to form the first ‘triple combos’ in melanoma.
For too many patients, the incredible responses they experience from targeted and immunotherapies don't last. Resistance is a real challenge. At the MRA 2019 Scientific Retreat, several researchers reported on research funded by MRA to identify new ways to combat drug resistance, including a number of strategies that are already being tested in the clinic.
Mohs Surgery for Melanoma In Situ – Where We Stand
While effective and time tested, Wide Local Excision can cause significant scarring and even loss of function when performed in delicate areas. For non-melanoma skin cancers, such as basal cell carcinomas and squamous cell carcinomas, an alternative ‘tissue-sparing’ procedure is frequently performed called Mohs Micrographic Surgery. Can Mohs Surgery be safely used in melanoma in situ?
Fighting For Her Life with a Clinical trial
Colleen Wittoesch was a regular volunteer at MD Anderson Cancer Center. She came to the hospital every week to help out and spend time with patients and families in the melanoma clinic for going on seven years. Little did she know that in 2016 she too would walk through the clinic doors as a patient.
Highlights from the 2019 Scientific Retreat
Over the course of three days, MRA convened over 300 people from across the melanoma research community: patients, doctors, researchers, industry, and government. Participants discussed everything from new treatment approaches such as RNA-based vaccines, strategies to fight back against treatment resistance, and hurdles to testing neo-adjuvant therapies in melanoma.
Clinical Trials to Watch: Turning Cold Tumors Hot
We know that the billions of bacteria that live in our bodies can impact the way we respond to immunotherapy, but can we harness this help more patients respond these life-saving drugs?
Police Lieutenant Tackles Melanoma in Phoenix
After being diagnosed with Stage 3 melanoma, Chris Eyrich is committed to raising awareness about melanoma. He works to raise awareness of the unique occupational hazards faced by people who work primarily outdoors, such as police officers and other public servants.
Research is Hope: MRA Announces $8.2 Million for New Grant Awards to Advance Melanoma Research
By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 30 April 2019 In News, Science
In advance of Melanoma Awareness Month, the Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research, today announced funding for 33 innovative research awards totaling $8.26 million.
Building Community While Raising More than $10 Million for Melanoma
By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 15 April 2019 In Allies & Partnerships, Events
Leveraged Finance Fights Melanoma has become an annual event that brings over 1,000 people together from the leveraged finance and private equity community. Cofounder Brendan Dillon shares his own journey with melanoma.
Melanoma Vaccines Show Promise
While immunotherapy has transformed way melanoma is treated, about half of patients still do not respond. Researchers are pursuing multiple strategies to understand why this happens and to develop strategies to jumpstart a response. One approach showing promise in early clinical trials, comes in the form of new personalized vaccines being developed by Ugur Sahin of Johannes Gutenberg-Universität Mainz and BioNTech.