On July 1st, MRA hosted another installment in our MRA Meet-Ups series, where we regularly connect with the melanoma community to discuss important topics, share insights and experiences, and ask questions. The session, called "Oncolytic Immunotherapy, Clinical Trials, & the Emerging RP1 Treatment", featured Dr. Yana Najjar of UPMC Hillman Cancer Center. Moderated by MRA’s Director of Communications and Engagement Dana Deighton, the discussion explored the science behind oncolytic immunotherapies, the critical role of clinical trial participation, and the promise of RP1 - a next-generation therapy being studied in combination with nivolumab for advanced melanoma as part of the ongoing IGNYTE-3 clinical trial (NCT06264180). This exciting combination is currently under priority review by the FDA, following the acceptance of a Biologics License Application (BLA) earlier this year. The BLA submission was supported by primary data from the IGNYTE clinical trial, and a final decision from the FDA is expected in the coming months. If approved, RP1 could be a groundbreaking new option for patients with advanced melanoma.
For those looking for a clinical trial option for patients with advanced melanoma that has progressed on certain immunotherapies (anti-PD-1 & anti-CTLA-4), please visit clinicaltrials.gov to learn about the ongoing IGNYTE-3 trial.