Melanoma is Determined, So is Eric
After 7 clinical trials, 8 surgeries, and more infusions than he can count --- Eric Martin is still here, seven years after being diagnosed with melanoma. He has had ups and downs and has tried practically every FDA-approved therapy for melanoma – but the crux of this story, which all readers need to understand, is that Eric’s fight isn’t yet finished. That’s because unlike many of the stories featured by MRA – Eric is still searching for his silver bullet and the elusive letters N.E.D. (no evidence of disease). He’s got big plans and melanoma isn’t going to get in the way. In short, Eric is a melanoma warrior.
Finding the Magic Formula
Modern immunotherapy, with melanoma as its poster child, is changing the way we treat cancer - for good. But, so far at least, it isn't helping everyone. Many scientists believe that there isn't a single silver bullet to unleash the awesome power of our immune systems - and instead - that the future of oncology is finding just the right combination of therapies that push and pull from different directions to multiply and enhance each other's effectiveness.
"I Thought I Knew Myself, but I Missed It."
Jim can’t say enough about his dermatologist who was able to detect his melanoma early enough so that more invasive treatment wasn’t necessary. “I see myself every day. I thought I knew myself, but I missed it. I see her twice a year, and those visits are quick, but she didn’t miss it. She was all over it.” The vigilance of his dermatologist may have saved Jim’s life.
We Challenge You! Join the Melanoma Research Alliance and the Your Cancer Game Plan Challenge!
We’re excited to announce that we’ve joined Merck on the Your Cancer Game Plan Challenge, a social sharing program that will help us raise funds and continue our support of melanoma patients, caregivers, healthcare providers and others.
The Hidden Costs of Cancer
The National Cancer Institute estimates that between 33 and 80% of cancer survivors exhaust their savings to finance their medical expenses. Up to three percent of survivors file for bankruptcy, 260 times more frequently than similar households not affected by cancer. Not only is this financially devastating for families, this hardship was the strongest predictor of the quality of life for cancer survivors.
The Microbiome, is it the Deciding Factor for Immunotherapy Success?
It's been nearly seven years since the first FDA-approved checkpoint inhibitor for melanoma came on the market and doctors, researchers, and patients all keep asking: "who is most likely to benefit from immunotherapy? How can we make this work for more people?" Thankfully, the answer may be closer than we thought and the trillions of bacteria, viruses, and other bugs - which make up our microbiome - may have something to say about it.
Creating a New Generation of Melanoma Models
We all can remember the eruption that happened when our 1st grade science teacher combined vinegar and baking soda together to represent a volcano. In some ways, this is just like experiments that take place every day in the search for better treatments, and ultimately a cure, for melanoma. In both instances, the researcher uses models to represent systems and phenomena that would otherwise be difficult or unethical to touch, see, or manipulate. Models are powerful things and we use them every day to make things easier to understand. In science, modeling is an essential component of our scientific process.
New Year, New Grantees An Insider's Perspective into MRA Grantmaking
New goals and time for personal reflection; the start of a year is an exciting time for many. It is also an action-packed time for the Melanoma Research Alliance's grantmaking process. As the Scientific Program Manager at MRA, I get a front row seat as we do our part to drive towards breakthroughs in the diagnosis, treatment, and prevention of melanoma.
FDA Approves Nivolumab in Adjuvant Setting - Is it a Big Deal?
By Louise M. Perkins, Ph.D., MRA Chief Science Officer | 21 December 2017 In News, Science, Treatment
The US FDA approved the use of nivolumab (Opdivo) in the adjuvant setting on December 20, 2017. This means that nivolumab may be used to treat melanoma patients with lymph node involvement or metastatic disease after complete surgical resection to reduce the risk of their disease recurring.
Introducing Clinical Trial Navigator: Start Searching Today
At MRA, we know that advancing science is our best bet in the fight against melanoma. More than 87,000 people in the US will be diagnosed with melanoma this year, and with these numbers on the rise, researchers are working harder than ever to find new and better treatment options. In fact, there are over 300 clinical trials happening in melanoma right now.