Category: Science


FDA Approves Nivolumab in Adjuvant Setting - Is it a Big Deal?

21 December 2017 In News, Science, Treatment

The US FDA approved the use of nivolumab (Opdivo) in the adjuvant setting on December 20, 2017. This means that nivolumab may be used to treat melanoma patients with lymph node involvement or metastatic disease after complete surgical resection to reduce the risk of their disease recurring.

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Introducing Clinical Trial Navigator: Start Searching Today

By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 5 December 2017 In Allies & Partnerships, News, Science, Treatment

At MRA, we know that advancing science is our best bet in the fight against melanoma. More than 87,000 people in the US will be diagnosed with melanoma this year, and with these numbers on the rise, researchers are working harder than ever to find new and better treatment options. In fact, there are over 300 clinical trials happening in melanoma right now.

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“Hands down, I’m alive today because of clinical trials”

By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 15 November 2017 In Melanoma Stories, Science

Jamie Goldfarb didn’t think of herself as having cancer. Yes, she had been diagnosed with Stage II melanoma four years earlier and Stage III the following year, but the surgeries to remove it had been successful. The PET scans that followed had been normal. This wasn’t supposed to be happening. Jamie was now a tired new mom with an eleven-week old baby and she was ready to get back to work. But, her world would turn upside down when she learned that not only was melanoma back, but it had progressed to Stage IV and spread to her liver and pancreas.

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Changing the Status Quo: Four Landmark Studies and their Implication for Melanoma Treatment

By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 13 November 2017 In News, Science

The crown jewel of the Melanoma Research Alliance has always been—and will always be—good science. Through science, we not only gain a better understanding of melanoma, but the ability to translate that understanding into better treatments, which in turn lead to a better quality of life for people with melanoma. At MRA, solid scientific leadership is at the forefront of everything we do. That’s why the MRA Board of Directors was thrilled to hear a presentation by fellow Board member and world-class researcher, Dr. Suzanne Topalian, on four landmark studies and their implications for melanoma treatment.

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Are Nanoparticles the Answer to the Question: Is it Working? An Interview with MRA Young Investigator, Dr. Ashish Kulkarni

By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 4 October 2017 In Science

When we think about cancer researchers, we don’t always think of engineers. Dr. Ashish Kulkarni proves that maybe, we should. His pioneering work as a chemical engineer is helping us answer the critical, yet difficult to answer question that is at the forefront of every patient’s mind as they start treatment: ‘is it working?’

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Measuring Progress: Skin Cancer Prevention in the United States

By Cody Barnett, MPH, MRA Director of Communications & Patient Engagement | 6 September 2017 In News, Prevention, Science

On July 29 2014, Dr. Boris Lushniak, the then acting U.S. Surgeon General at, issued a landmark call to action when he declared skin cancer as a major public health problem. He called on everyone, from government agencies to community-based organizations to schools to come together to increase awareness of skin cancer and ways to reduce risk. Since the Call to Action, The Centers for Disease Control and Prevention (CDC) has released an annual report each year documenting progress, celebrating success, and identifying areas where improvement is needed. The key areas of the Call to Action and the update from the CDC 2017 Progress Report are highlighted below.

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L’Oréal Paris USA-MRA Team Scientists shed light on how melanoma spreads

By Kristen Mueller, PhD | 29 August 2017 In Allies & Partnerships, Science, Treatment

MRA is extremely proud of the 289 investigators we have funded over the last decade and the exciting advances they have made toward ending suffering and death due to melanoma. While we can never highlight all of them at one time, we’re excited in this blog to highlight the work of the L’Oreal Paris USA sponsored MRA Team award.

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Why so much excitement about CAR-T cells?

By Kristen Mueller, PhD | 18 July 2017 In News, Science, Treatment

July 12, 2017, marked a historic day for medicine and for the US Food and Drug Administration (FDA) when an expert advisory committee to the FDA unanimously endorsed the first ever genetically engineered, cell-based therapy for use in patients.

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Melanoma Treatments: Breakthroughs for Multiple Cancers — for Real and Right Now

10 July 2017 In Science, Treatment

While 2014 and 2015 offered a whirlwind of good news related to new melanoma treatments from immune to targeted therapy, since then, it’s been a bit quieter in melanoma. Although there has been exceptional news in regard to other cancers. Why is that, and what are the latest breakthroughs?

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Melanoma Research Alliance and the American Cancer Society Forge Research Partnership to Maximize Immunotherapy Benefit to Patients

By Pamela Goldsmith, MRA Director of Communications | 10 July 2017 In Allies & Partnerships, Science

The Melanoma Research Alliance (MRA) and the American Cancer Society (ACS) are partnering to fund much-needed research aimed at decreasing rare, but serious, side effects associated with checkpoint inhibitors in hopes of increasing further cancer immunotherapy benefit to patients.

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