Category: Science


2021 AACR and ASCO Melanoma Highlights

By Marc Hurlbert, PhD, MRA Chief Executive Officer | 29 June 2021 In News, Science, Treatment

Over the last few months, thousands of scientists and physicians from around the globe gathered virtually for two of the largest cancer research conferences – AACR and ASCO. Melanoma research advances were showcased at both events and it’s an exciting time with numerous presentations of clinical trials for new melanoma treatments. Here we highlight some of the most exciting results from both conferences.

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New Immunotherapy Drugs Targeting LAG-3 Show Great Promise

By Kristen Mueller, PhD | 23 June 2021 In News, Science, Treatment

Researchers presented a series of highly encouraging clinical trial results at the recent American Society for Clinical Oncology (ASCO) annual meeting that suggest that new drugs targeting the protein LAG-3 – developed by BMS and Regeneron – may be an important addition to the current treatment arsenal.

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Averting and Treating Immune-related Adverse Events Associated with Checkpoint Immunotherapies

14 June 2021 In Science, Treatment

Checkpoint inhibitors are therapies that empower the immune system to kill cancer cells. However, sometimes immune-related adverse events (irAE) can also occur as a result. To help overcome this challenge, MRA has issued a number of research grants, including some in partnership with the American Cancer Society (ACS) and the Society for Immunotherapy of Cancer (SITC), to support an array of approaches.

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Advancing Melanoma Research in Times of Uncertainty

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 9 June 2021 In Allies & Partnerships, Melanoma Stories, Policy, Prevention, Science, Treatment

Each year, the annual MRA Scientific Retreat brings hundreds of people from across the melanoma research ecosystem together to exchange ideas, report on scientific progress, celebrate achievements, and mourn the losses. In these ways, the 2021 Retreat was no different.

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Separating Hope From Hype in Melanoma Research

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 4 June 2021 In Science, Treatment

In the last decade alone 13 therapeutic approaches have earned FDA approval giving patients, families, and clinicians new tools to treat melanoma. But there can be a fine line between hope and hype, especially today when news — both true and inflated — travels instantly via the internet and social media.

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MRA's Acral Melanoma Cell Line Catalog: A Launching Pad for Research

By Raj Talukdar, MRA Science Intern | 25 May 2021 In Science

In a collaborative effort to facilitate research focused on acral melanoma, MRA has created and annotated a catalog of acral melanoma cell lines from various institutions worldwide. The catalog includes cell lines created by researchers at Memorial Sloan Kettering Cancer Center, Wistar Institute, Yale University, the University of Zurich, the Queensland Institute of Medical Research in Australia and more.

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Firming the Foundation: Pathology, Rare Melanomas, and Moving the Field Forward

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 21 May 2021 In Science, Treatment

When Dr. Priyadharsini Nagarajan talks about her work at MD Anderson Cancer Center, her energy and excitement could light up any room. That’s because Dr. Nagarajan – a pathologist who specializes in skin (called a ‘dermatopathologist’) – sees her work as critical to creating a firm foundation for all subsequent...

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Melanoma Research Alliance Announces $8.1 million in Research Awards

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 27 April 2021 In News, Prevention, Science, Treatment

The Melanoma Research Alliance, the largest non-profit funder of melanoma research, is proud to announce $8.1 million in funding for 34 new research awards. The awards, issued on the cusp of Melanoma Awareness Month, provide critical funding to address urgent unmet needs in melanoma.

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A New Treatment Approach in the Arsenal: Neoadjuvent Therapy

23 April 2021 In Allies & Partnerships, News, Science, Treatment

Surgery is the backbone of melanoma treatment and is curative for the vast majority of patients with localized melanoma. However, even if surgery successfully removes all detectible traces of tumor tissue, some patients will still experience a melanoma relapse. Can neoadjuvant therapy, an experimental approach, reduce the risk of recurrence?

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UV Exposure & Risk of Cutaneous Melanoma in Skin of Color

By Rachel Fischer, Ph.D., Associate Director, Scientific Program & Registry | 14 April 2021 In News, Prevention, Science

In JAMA Dermatology, a team led by Adewole S. Adamson, MD, from The University of Texas at Austin, investigates whether there is an association, specifically in People of Color, between UV exposure and melanoma. MRA breaks down what this research means and how it should impact your sun safety practices.

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